Restore smoother texture, improved tone, and youthful volume using your body’s own regenerative power. PRFM face injection supports collagen renewal for natural results that strengthen skin from within.
Revitalize Skin With a Natural Regeneration Approach
PRFM injection is a skin rejuvenation treatment for patients seeking subtle, biologically driven improvements without fillers or synthetic ingredients. At StudioMD in NYC, we use the Selphyl system to process your own platelets into a Platelet Rich Fibrin Matrix that supports collagen renewal and visible skin rejuvenation.
Many patients choose PRFM injections because it blends natural healing processes with measurable aesthetic benefits. It enhances firmness, softens fine lines, and improves overall skin quality while maintaining facial character and expression.
Cost:
Face injection (2 tubes) $1,020
New Clients (15% off) $867
Members (20% off) $816
What Is PRFM Skin Rejuvenation?
PRFM stands for Platelet Rich Fibrin Matrix, a formulation created from a small sample of your own blood. Once processed through the Selphyl system, the platelets release growth factors gradually over several days.
These factors stimulate collagen production, support cell repair, and help rebuild the extracellular matrix, contributing to healthier, more youthful-looking skin.
PRFM Injection Procedure Details
How PRFM Works at the Cellular Level
PRFM is prepared by processing your blood in a specialized Selphyl device. The system concentrates platelets and forms a fibrin matrix that protects and stabilizes the growth factors. When injected just beneath the skin, PRFM releases these factors slowly, supporting collagen remodeling for days after treatment rather than minutes.
What Happens During the Appointment
Your provider draws a small amount of blood, processes it in the Selphyl centrifuge, and prepares the PRFM for injection. The treatment areas are cleansed, and the PRFM is placed strategically to support volume and texture. Most patients find the procedure comfortable, especially with topical numbing as needed.
Where PRFM Is Most Commonly Used
PRFM improves texture and volume in areas such as the cheeks, tear troughs, jawline, temples, and around the mouth. It can also enhance skin quality in the neck and décolletage. Because it is autologous, PRFM is often chosen by patients seeking a natural alternative to fillers.
How PRFM Stimulates Visible Improvement
Once administered, PRFM begins releasing growth factors over a period of up to seven days. This prolonged activation encourages collagen rebuilding and tissue repair. Patients often see soft, natural improvements in tone, elasticity, and volume within several weeks, with continued enhancement over time.
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I cannot recommend Studiomd highly enough! The service was truly amazing from the moment I walked in—professional, welcoming, and incredibly relaxing—and it absolutely exceeded all my expectations. The real highlight was my esthetician, Merve, who did a very good job; she was meticulous, took the time to explain everything clearly, and provided the most expert care I've ever received, leading to fantastic results. If you are planning a visit to Studiomd, I strongly encourage you to book with Merve, as she is an absolute star and a highly skilled esthetician!
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I had such an amazing experience! Jennifer made me feel completely comfortable from start to finish. My laser treatments were super effective, and the Clear & Brilliant treatment has already made a huge difference in my hyperpigmentation. She’s knowledgeable, gentle, and truly cares about your skin goals. Highly recommend!
“Merve is the best esthetician!! I’ve been seeing Merve for microneedling and Clear + Brilliant treatments, and the results have been amazing! My skin has never looked better—glowing, smooth, and refreshed. Merve is incre...”
Merve is the best esthetician!! I’ve been seeing Merve for microneedling and Clear + Brilliant treatments, and the results have been amazing! My skin has never looked better—glowing, smooth, and refreshed. Merve is incredibly knowledgeable, professional, and makes every session comfortable and personalized. I highly recommend her to anyone looking for expert skincare treatments with visible results!
“I’ve been going to StudioMD for over two years now. I see Natalia for laser hair removal and for facials. She is awesome! Best facials ever!”
“The best aesthetician experience in NYC! I can’t say enough amazing things about my experience at this spa. From the moment I walked in, I was greeted with such warmth and professionalism. The space is beautiful, clean, ...”
The best aesthetician experience in NYC! I can’t say enough amazing things about my experience at this spa. From the moment I walked in, I was greeted with such warmth and professionalism. The space is beautiful, clean, calming, and thoughtfully designed; but what truly sets it apart is Merve. She took the time to really assess my skin, asked all the right questions, and explained every step of the treatment in detail. Her technique was gentle yet incredibly effective. I left glowing, refreshed, and honestly feeling like a new person. She customized everything for my skin type and even gave me at home care recommendations that actually work. To add on I also did laser with her which was also an amazing and smooth experience. It’s rare to find someone who combines skill, knowledge, and genuine care the way she does. You can tell she’s passionate about what she does, and it shows in the results. My skin has never looked better, and I’m officially hooked. If you’re in NYC and looking for a facial or skincare treatment that feels luxurious and delivers real results, this is the place & Merve is your girl!
“Ellie is the kind of esthetician you spend a lifetime trying to find. She's is beyond knowledgeable in her craft and I trust her implicitly with my treatments + skincare recommendations. My skin has done a total 180 sinc...”
Ellie is the kind of esthetician you spend a lifetime trying to find. She's is beyond knowledgeable in her craft and I trust her implicitly with my treatments + skincare recommendations. My skin has done a total 180 since I've been in her care and I recommend her to everyone I know. She is always warm and welcoming and has me leaving the spa feeling confident and relaxed as any spa experience should. The spa is beautiful, clean, organized, and well run. Will be returning and recommending to friends!
“I strongly recommend this location Jaime is very knowledgeable and sweet, I came in for a consultation and will start a láser package and skin rejuvenation”
“I travel from the city to receive treatments from Alex at StudioMD Larchmont. She is so talented and worked her magic to take years off my face. I did a Morpheus8 package with her to tighten skin, produce collagen and he...”
I travel from the city to receive treatments from Alex at StudioMD Larchmont. She is so talented and worked her magic to take years off my face. I did a Morpheus8 package with her to tighten skin, produce collagen and help with texture. I also do regular HydraFacial ’s with Laser Genesis. My skin has completely changed since I started seeing Alex. I highly recommend Alex and StudioMD! Thank you, Alex!
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I absolutely love Studio MD — but what truly makes it worth the hour-long commute is Alex. She made me feel completely at ease during my very first session and has been incredible ever since. Her professionalism, kindness, and attention to detail are unmatched. The location itself is always spotless, which is a huge plus for me. If you’re looking for the right place for laser treatments, this is it. And trust me — once you meet Alex, you won’t want to go anywhere else!
“I've been a client for quite a while and have done a few procedures at this location, specifically with the RN Maria and every single visit was patient and attentive Maria explained things clearly. I trust and recommend ...”
I've been a client for quite a while and have done a few procedures at this location, specifically with the RN Maria and every single visit was patient and attentive Maria explained things clearly. I trust and recommend her services above all. and all my results had productive outcomes. I am still a client and continue to get services from this establishment and Maria. I highly recommend.
“Amazing doctors and staff. I would def recommend. Doctors and Staff are very knowledgeable would def recommend.”
“I have been a client in the Mendham office for a few years. It’s the only medical spa I will go to. Kelly is the best. Great bedside manner. She takes time to listen and comes up with a plan to meet your needs. From faci...”
I have been a client in the Mendham office for a few years. It’s the only medical spa I will go to. Kelly is the best. Great bedside manner. She takes time to listen and comes up with a plan to meet your needs. From facials, to NAD injections to body sculpture , she is your girl! I give her a 10 plus.
“I have seen Dr. Sanja Kolarov and she is very professional with excellent manners towards her patients. She takes the time to explain the possible treatment plans and advises the most appropriate for her patients. She is...”
I have seen Dr. Sanja Kolarov and she is very professional with excellent manners towards her patients. She takes the time to explain the possible treatment plans and advises the most appropriate for her patients. She is very thorough, an excellent physician and person . Had a procedure done by her and I am very satisfied. I highly recommend her
“Dr. Kolarov is very kind and efficient at her job. Her staff provided great service. they are all very friendly and accommodating.”
“Dr.Kolarov is amazing! She is professional and informative. I'm getting great results with my treatments! The facility is very clean, and the customer service is excellent! I would highly recommend Dr. Kolarov !”
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“I had such a wonderful experience at StudioMD. The staff was warm, professional, and made me feel completely comfortable! The space was clean and beautifully maintained. My consultation was thoroughly explained, personal...”
I had such a wonderful experience at StudioMD. The staff was warm, professional, and made me feel completely comfortable! The space was clean and beautifully maintained. My consultation was thoroughly explained, personalized to my needs, and the results were even better than I expected. I truly appreciated the attention to detail and the genuine care that Jennifer put into every step. I highly reccomend!
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“I cannot express enough how grateful I am for Jaime and the incredible support she has provided throughout what has been a very difficult journey for me. From the very first moment, she demonstrated not only outstanding ...”
I cannot express enough how grateful I am for Jaime and the incredible support she has provided throughout what has been a very difficult journey for me. From the very first moment, she demonstrated not only outstanding professionalism but also a level of kindness and compassion that truly set her apart. Jaime’s knowledge and expertise are evident in everything she does. She takes the time to explain each step clearly, answers every question with patience, and makes sure you feel completely supported and informed throughout the process. What could have been an overwhelming experience was made manageable—honestly, even comforting—because of her. Her warmth and genuine care have made such a difference in my experience. I only wish I had found this place—and Jaime—sooner. She is truly a rare gem, and I can’t thank her enough for everything she has done for me. If you’re considering coming here, know that you’ll be in the best possible hands with Jaime.
“I’ve been going to this studio MD location for almost two years now, and get treatments done regularly by Dr. Corson. She’s been a great provider! She’s kind and patient when you ask questions, and she is incredibly effi...”
I’ve been going to this studio MD location for almost two years now, and get treatments done regularly by Dr. Corson. She’s been a great provider! She’s kind and patient when you ask questions, and she is incredibly efficient at what she does. The staff here and the receptionists are also very kind and accommodating. I cannot recommend both Dr. Corson and studio MD enough!
“My favorite, go to place in the city!!! Clean, the best service & results. Thank you guys 🫶🏼✨✨”
Recovery After PRFM Skin Rejuvenation
PRFM involves minimal downtime, making it suitable for patients with active schedules. Mild swelling, redness, or tenderness may occur around injection sites but typically resolves within one to two days. Because PRFM uses your own platelets, the risk of sensitivity or reaction is extremely low.
Your provider will recommend simple aftercare, such as avoiding vigorous exercise for 24 hours and keeping the skin clean. Most individuals return to work or social activities immediately, with early improvements visible in the first week.
Your PRFM Skin Rejuvenation Results
Results develop gradually as collagen rebuilds. Many patients notice subtle volume enhancement, firmer texture, and improved tone within several weeks. PRFM is not permanent, but effects can last several months, especially when incorporated into a broader skin maintenance plan. Periodic treatments help sustain collagen support and maintain a refreshed appearance.
Why Choose StudioMD?
StudioMD has spent nearly 20 years refining regenerative and aesthetic treatments for patients across NYC. Our medical doctors, including plastic and cosmetic surgeons, bring extensive experience to PRFM and other biologic procedures that rely on careful technique and detailed anatomical understanding.
Because StudioMD has performed hundreds of thousands of aesthetic treatments, we are highly experienced at assessing skin quality, selecting the right candidates, and customizing treatment plans for long-term improvement. Our focus is on natural results, transparency, and individualized guidance, helping each patient understand what PRFM can and cannot achieve before treatment begins.
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Dr. Ali Khan, with 18+ years in aesthetics, is a Smartlipo pioneer with 5,000+ procedures performed. He specializes in liposuction, injectables, hair restoration, and minor surgical treatments.
Dr. Sadaf Qazi, DO
Cosmetic Surgeon
Dr. Sadaf Qazi is a skilled cosmetic surgeon specializing in body contouring, facial procedures, and injectables. Her expertise spans tummy tucks, BBL, liposuction, breast augmentation, blepharoplasty, and advanced dermal filler techniques.
Dr. Amar Singh, MD
Plastic Surgeon
Dr. Amar Singh is a board-certified plastic surgeon with over 20 years of experience. Trained in multiple fellowships, he specializes in facial plastic surgery, liposuction, injectables, and advanced laser treatments, while actively teaching future surgeons.
Dr. Sanja Kolarov, MD
Board-Certified Physician
Dr. Sanja Kolarov, a board-certified physician with 17+ years of experience, specializes in injectables, laser treatments, liposuction, hair restoration, and regenerative therapies, providing patients with advanced, medically guided aesthetic care and natural results.
Dr. Kathryn Alcarez, MD
Physician
Dr. Kathryn Alcarez is an experienced Primary Care Physician with 13+ years of experience and specializes in dermal fillers, wellness, and skin rejuvenation treatments. Her caring approach to her patients is to provide the best preventative care modalities and evidence based medicine possible to maintain their long term health and wellness.
Dr. Meredith Corson, DO
Board-Certified Physician
Dr. Meredith Corson is a seasoned Primary Care Physician specializing in anti-aging medicine, promoting both internal and external wellness. With over 16 years of experience, she has honed skills in toxins applications, biostimulator fillers, and wellness treatments, earning a solid reputation in facial aesthetics.
Vanessa Sanchez, NP
Board-Certified Nurse Practitioner
Vanessa Sanchez, a board-certified nurse practitioner with 8+ years of experience, specializes in women’s health, injectables, and advanced anti-aging. She also provides personalized weight loss treatments designed to support long-term aesthetic and wellness goals.
Dr. Afnan Talat, MD
Board-Certified Physician
Dr. Afnan Talat, a board-certified physician with 9+ years of experience, specializes in aesthetics, weight loss, and sexual health. Her background in skincare science informs her expertise in botox, fillers, and anti-aging medicine.
Dr. Jeena Zachariah, MD
Board-Certified Physician
Dr. Jeena Zachariah is a board-certified physician with over five years experience in aesthetic medicine. She excels in facial optimization through the use of neuromodulators and dermal fillers, performs radiosurgeries, body contouring injections and hair restoration surgeries, demonstrating a keen eye for detail in every procedure.
Maria Rivera, RN
Clinical & Operations Director for Hair Restoration
Maria Rivera has over twenty years of experience in the medical field and hair restoration and is a leading expert in FUE, FUT, hair injections and everything else about hair loss treatments and procedures.
Krystelle Afif, NP
Nurse Practitioner
Krystelle is a board-certified Nurse Practitioner known for her natural-looking results and personalized approach. With a strong foundation in anatomy and precision techniques, she specializes in injectables such as Botox, Fillers, Sculptra, and Radiesse.
Niki Ioannou, NP
Nurse Practitioner
Niki Ioannou specializes in advanced injectables including Botox, Fillers, Sculptra, and Radiesse, as well as non-surgical weight loss treatments. Known for her precision and personalized care, Niki combines technical expertise with a deep understanding of facial anatomy to help patients look and feel their best.
Dr. Lena Makartian, MD
Physician
Dr. Lena Makartian is a board‑certified Primary Care Physician with over five years of clinical experience. She specializes in injectables, laser treatments, skin rejuvenation, body contouring, hair restoration, wellness and weight-management therapies, offering patients comprehensive, medically guided aesthetic care.
Dr. Sarah Margolskee, MD
Physician
Dr. Sarah Margolskee is a board-certified physician with over 5 years of experience specializing in wellness, injectables, and aesthetic medicine. Her clinical background informs her precise approach to skin lesions, mole removal, and personalized weight loss treatments designed to support long-term health and confidence.
Dr. Louis Mariotti, DO
Board Certified Plastic Surgeon
Dr. Mariotti is a Board Certified Plastic Surgeon, specialist in Hair Restoration Medicine and Surgery. With over 30 years of experience and a strong background in facial plastic surgery and hair restoration, he has trained and instructed other surgeons at leading conferences and has been actively involved in advancing techniques within the field.
Madisyn Ferone, NP
Nurse Practitioner
Madisyn Ferone is a Board-Certified Nurse Practitioner. She specializes in advanced injectables including Botox, Fillers, Sculptra, and Radiesse. Madisyn brings a patient-centered aesthetic care, and evidence-based beauty enhancements. Passionate about helping patients feel confident through natural-looking results while combining advanced clinical expertise with personalized treatment planning.
PRFM is created from your own blood using the Selphyl system. It produces a concentrated platelet matrix that releases growth factors gradually to support collagen renewal and tissue repair.
Where can PRFM be applied?
PRFM is commonly used on the face, including the tear troughs, cheeks, and jawline. It may also rejuvenate areas such as the neck and chest, depending on your goals.
Is PRFM safe for all skin types?
Yes. Because PRFM uses your own platelets without additives, it is widely considered safe for all skin tones and types, with very low risk of reaction or sensitivity.
How soon will I see improvement?
Mild improvement often appears quickly, but collagen building takes time. Many patients see more noticeable results within three weeks, with continued enhancement as the matrix releases growth factors.
How many treatments will I need?
Some patients see meaningful results from a single session, while others prefer a series spaced several months apart. Your provider will review options and create a personalized plan.
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